发明名称 |
Method of producing L-serine by fermentation |
摘要 |
L-serine is produced by cultivating in a medium a coryneform bacterium having L-serine productivity in which an activity of at least one of phosphoserine phosphatase and phosphoserine transaminase is enhanced, preferably, further having introduced therein a gene coding for D-3-phosophoglycerate dehydrogenase in which feedback inhibition by L-serine is desensitizied, allowing L-serine to accumulate in the medium, and collecting the L-serine from the medium. |
申请公布号 |
EP0931833(A2) |
申请公布日期 |
1999.07.28 |
申请号 |
EP19990100325 |
申请日期 |
1999.01.12 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
SUGA, MIKIKO;SUGIMOTO, MASAKAZU;OSUMI, TSUYOSHI;NAKAMATSU, TSUYOSHI;HIBINO, WATARU;ITO, MIKA |
分类号 |
C12N15/09;C12N1/20;C12N1/21;C12N9/04;C12N15/53;C12P13/06;C12R1/13 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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