| 发明名称 |
ANTI-INFLAMMATORY AGENTS |
| 摘要 |
Compounds of general formula (I) wherein R4 is an ester or thioester group and R, R1, R2, and R3 are as specified in the description, inhibit intracellular Leukotriene A4 hydrolase activity and are therefore of value for the treatment of inflammatory disease.
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| 申请公布号 |
WO9940910(A1) |
申请公布日期 |
1999.08.19 |
| 申请号 |
WO1999GB00284 |
申请日期 |
1999.01.27 |
| 申请人 |
BRITISH BIOTECH PHARMACEUTICALS LIMITED;AYSCOUGH, ANDREW, PAUL;WHITTAKER, MARK |
发明人 |
AYSCOUGH, ANDREW, PAUL;WHITTAKER, MARK |
| 分类号 |
C07D253/06;A61K31/215;A61K31/216;A61K31/22;A61K31/223;A61K31/341;A61K31/381;A61K31/4015;A61K31/403;A61K31/4035;A61K31/4162;A61K31/4166;A61K31/4245;A61K31/435;A61K31/437;A61K31/4402;A61K31/4406;A61K31/445;A61K31/4465;A61K31/45;A61K31/53;A61P1/04;A61P11/06;A61P17/00;A61P17/04;A61P17/06;A61P19/02;A61P25/00;A61P29/00;C07D207/27;C07D207/408;C07D211/46;C07D211/88;C07D213/40;C07D221/10;C07D233/96;C07D263/44;C07D271/06;C07D307/20;C07D333/24;C07D333/34;C07D471/04;C07D487/04;(IPC1-7):A61K31/215;A61K31/38;A61K31/34;A61K31/44 |
主分类号 |
C07D253/06 |
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