发明名称 |
Fusion proteins comprising gp39 and CD8 |
摘要 |
The present invention relates to fusion proteins having gp39 protein sequences, which fusion proteins bind to the B cell antigen, CD40. More specifically, the invention relates to fusion proteins having gp39 protein sequences attached to a polypeptide having an amino terminal secretory signal sequence to allow export of the fusion protein out of the recombinant host cell in which it is produced. The fusion proteins of this invention may be useful for promoting B cell proliferation.
|
申请公布号 |
US5945513(A) |
申请公布日期 |
1999.08.31 |
申请号 |
US19960690096 |
申请日期 |
1996.07.30 |
申请人 |
BRISTOL-MYERS SQUIBB |
发明人 |
ARUFFO, ALEJANDRO;HOLLENBAUGH, DIANE;LEDBETTER, JEFFREY A. |
分类号 |
A61K38/00;A61K39/395;A61P37/04;A61P43/00;C07K14/00;C07K14/47;C07K14/52;C07K14/705;C07K14/725;C07K16/28;C07K19/00;C12N5/06;C12N15/09;C12N15/12;C12P21/02;C12P21/08;(IPC1-7):C07K19/00 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|