发明名称 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE N-BENZYL-3-PYRROLIDINOL
摘要 <p>The invention provides an efficient method of producing optically active N-benzyl-3-pyrrolidinol by an enzymatic reaction stereoselectively reducing N-benzyl-3-pyrrolidinone. The invention consists in a method of producing optically active N-benzyl-3-pyrrolidinol which comprises a step of obtaining a reaction mixture by treating N-benzyl-3-pyrrolidinone with cells or a culture of a microorganism, or a material derived therefrom, and a step of recovering optically active N-benzyl-3-pyrrolidinol from said reaction mixture, in which method said microorganism mentioned above is a microorganism belonging to the genus Depodascus, Debaryomyces, Cryptococcus, Pichia, Rhodosporidium, Trichosporon, Micrococcus, Komagataella, Ogataea or Zygosaccharomyces.</p>
申请公布号 EP0942068(A1) 申请公布日期 1999.09.15
申请号 EP19970946058 申请日期 1997.11.26
申请人 KANEKA CORPORATION 发明人 YASOHARA, YOSHIHIKO;HASEGAWA, JUNZO
分类号 C07D207/12;C12P17/10;C12P41/00;C12R1/265;C12R1/645;C12R1/84;(IPC1-7):C12P17/10 主分类号 C07D207/12
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