Auf einem poröser Träger gebundene Polysaccharide, Verfahren zu deren Herstellung und ihre Verwendungen

摘要

A novel substance having a main structure represented by the following Formula: Also disclosed are a method of producing the substance in which an oligosaccharide having a degree of polymerization from 3 to 10 is chemically bonded to a silane agent at the reducing terminal of the oligosaccharide, the oligosaccharide derivative obtained is polymerized to an average degree of polymerization from about 11 to about 500 with the action of an enzyme; and a method in which the aldehyde group present at the reducing terminal of an oligosaccharide having a degree of polymerization from 3 to 10 is oxidized with an oxidizing agent, and the saccharide chain of the oxidized product is polymerized to a degree of polymerization from about 11 to about 500 by the action of an enzyme, followed by the addition of an acid. The substance is excellent in solvent resistance and useful as a separating agent for chromatography, in particular, for the separation of chiral compounds.