发明名称 |
Thiazolidinedione derivatives or salts thereof and pharmaceutical compositions containing the same |
摘要 |
This invention relates to a thiazolidinedione derivative represented by the following formula (1): wherein R1 and R2 individually represent H, a halogen atom, or a halogen-substituted or -unsubstituted lower alkyl or alkoxy group, and R1 and R2 may be coupled together to form a ring of an alkylenedioxy chain, X represents a nitrogen atom or a CH group, A represents a substituted or unsubstituted imidazolidinone, pyrrolidinone, imidazole or pyrazole ring, or a salt thereof; and a pharmaceutical composition containing the thiazolidinedione derivative or a salt thereof. The above compound has excellent blood sugar-lowering action and blood lipid-lowering action and is useful as a therapeutic agent for diabetes.
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申请公布号 |
US5990139(A) |
申请公布日期 |
1999.11.23 |
申请号 |
US19960655644 |
申请日期 |
1996.05.30 |
申请人 |
TAIHO PHARMACEUTICAL CO., LTD. |
发明人 |
YANO, SHINGO;OGAWA, KAZUO;FUKUSHIMA, MASAKAZU |
分类号 |
A61K31/425;A61K31/44;A61P3/08;A61P3/10;C07D207/26;C07D207/27;C07D231/12;C07D233/32;C07D233/54;C07D401/04;C07D403/04;C07D417/12;C07D417/14;(IPC1-7):C07D417/12 |
主分类号 |
A61K31/425 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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