发明名称 |
E2F ACTIVITY INHIBITORY COMPOUNDS |
摘要 |
<p>Compounds represented by the general formula (I): R<1>-A-R<2> or pharmacologically acceptable salts thereof wherein R<1> represents (un)substituted alkanoyl, (un)substituted aroyl, (un)substituted heteroarylcarbonyl, (un)substituted alkoxycarbonyl, (un)substituted aryloxycarbonyl, (un)substituted heteroaryloxycarbonyl, or hydrogen; R<2> represents hydroxy, (un)substituted alkoxy or (un)substituted amino; and A represents a partial peptide sequence comprising at least 12 consecutive amino acid residues in the sequence of a dimer forming or DNA binding region of each member of E2F family.</p> |
申请公布号 |
EP0963999(A1) |
申请公布日期 |
1999.12.15 |
申请号 |
EP19970941259 |
申请日期 |
1997.09.26 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
SHIBATA, KENJI;YAMASAKI, MOTOO;YOSHIDA, TETSUO;MIZUKAMI, TAMIO |
分类号 |
A61K38/00;C07K14/47;(IPC1-7):C07K14/47;A61K38/17 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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