Nitric oxide synthase inhibitors

摘要

The present invention relates to novel amidino compounds of formula (I),or a salt, solvate, or physiologically functional derivative thereof;wherein R1 is selected from C1-4 alkyl, C3-4 cycloalkyl, C1-4 hydroxyalkyl, and C1-4 haloalkyl; to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible nitric oxide synthase.