发明名称 |
Stable no-delivering compounds |
摘要 |
Disclosed are novel NO-releasing compounds which comprise a stabilized S-nitrosyl group and a free alcohol or a free thiol group. Also disclosed is a method of preparing the NO-releasing compounds. The method comprises reacting a polythiol or a thioalcohol with a nitrosylating agent. Also disclosed are medical devices coated with the disclosed compounds, methods of delivering NO to treatments sites in a subject by utilizing the medical devices and methods of sterilizing surfaces. |
申请公布号 |
AU4580599(A) |
申请公布日期 |
2000.01.10 |
申请号 |
AU19990045805 |
申请日期 |
1999.06.21 |
申请人 |
DUKE UNIVERSITY MEDICAL CENTER |
发明人 |
ERIC J. TOONE;JONATHAN S STAMLER |
分类号 |
A61L2/16;A61F2/02;A61K31/095;A61L2/20;A61L2/23;A61L29/16;A61P31/04;A61P43/00;C07C381/00 |
主分类号 |
A61L2/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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