发明名称 Stable no-delivering compounds
摘要 Disclosed are novel NO-releasing compounds which comprise a stabilized S-nitrosyl group and a free alcohol or a free thiol group. Also disclosed is a method of preparing the NO-releasing compounds. The method comprises reacting a polythiol or a thioalcohol with a nitrosylating agent. Also disclosed are medical devices coated with the disclosed compounds, methods of delivering NO to treatments sites in a subject by utilizing the medical devices and methods of sterilizing surfaces.
申请公布号 AU4580599(A) 申请公布日期 2000.01.10
申请号 AU19990045805 申请日期 1999.06.21
申请人 DUKE UNIVERSITY MEDICAL CENTER 发明人 ERIC J. TOONE;JONATHAN S STAMLER
分类号 A61L2/16;A61F2/02;A61K31/095;A61L2/20;A61L2/23;A61L29/16;A61P31/04;A61P43/00;C07C381/00 主分类号 A61L2/16
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