发明名称 |
PROGRAMMED CELL DEATH AND CASPASE-12 |
摘要 |
This invention relates to nucleic acids encoding caspase-12, proteins encoded by casp-12 nucleic acids, vectors, and hosts transformed with vectors. Caspase-12 is a member of the caspase family, which also includes mammalian interleukin-1 beta -converting enzyme (ICE). Caspases are thought to carry out the execution phase of apoptosis in a cascade of proteolytic events. The invention also relates to the use of caspase-12 to induce programmed cell death.
|
申请公布号 |
WO9952925(A9) |
申请公布日期 |
2000.01.27 |
申请号 |
WO1999US08064 |
申请日期 |
1999.04.14 |
申请人 |
THE GENERAL HOSPITAL CORPORATION;YUAN, JUNYING;MORISHIMA, NOBUHIRO |
发明人 |
YUAN, JUNYING;MORISHIMA, NOBUHIRO |
分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K48/00;A61P35/00;A61P43/00;C07H21/04;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/50;C12N9/64;(IPC1-7):C07H21/04;C12Q1/68;C12Q1/37;C12N15/00;C12N1/20 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|