| 发明名称 |
RECOMBINANT METHODS AND MATERIALS FOR PRODUCING EPOTHILONE AND EPOTHILONE DERIVATIVES |
| 摘要 |
Recombinant nucleic acids that encode all or a portion of the epothilone polyketide synthase (PKS) of sorangium cellulosum are used to express recombinant PKS genes in host cells for the production of epithilones, epothilone derivatives, and polyketides that are useful as cancer chemotherapeutics, fungicides, and immunosuppressants.
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| 申请公布号 |
WO0031247(A2) |
申请公布日期 |
2000.06.02 |
| 申请号 |
WO1999US27438 |
申请日期 |
1999.11.19 |
| 申请人 |
KOSAN BIOSCIENCES, INC. |
发明人 |
JULIEN, BRYAN;KATZ, LEONARD;KHOSLA, CHAITAN;TANG, LI;ZIERMANN, RAINER |
| 分类号 |
C12N15/09;A61K31/365;A61K31/427;A61K31/529;A61K31/537;A61P35/00;A61P43/00;C07D277/22;C07D277/28;C07D313/00;C07D417/06;C07D493/04;C07D493/08;C07D498/08;C07D513/08;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N15/52;C12P17/16;C12P17/18;C12R1/38;(IPC1-7):C12N15/00 |
主分类号 |
C12N15/09 |
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