IMPROVED PRODUCTS AND METHODS FOR THE REMINERALIZATION AND PREVENTION OF DEMINERALIZATION OF TEETH

摘要

PURPOSE: Improved products and methods for remineralizing subsurface lesions in teeth and for mineralizing exposed tubules in dentin are provided to prevent demineralization thereof. CONSTITUTION: A liquid product for remineralizing subsurface lesions and/or for mineralizing exposed dentin tubules in teeth, comprises: (a) a cationic component comprising at least one partially water-soluble calcium salt; (b) an anionic component comprising at least one water-soluble phosphate salt and at least one water-soluble fluoride salt; and (c) a separating means disposed to separate the components (a) and (b), wherein the components (a) and (b) have a pH in water such that a mixed aqueous composition formed by mixing the components (a) and (b) with water and/or saliva has a pH of from about 4.0 to about 10.0; further wherein the product contains an amount of the calcium salt such that in the mixed aqueous composition a first portion of the calcium salt exists as dissolved calcium cations and a second portion of the calcium salt exists as undissolved calcium salt, the aqueous composition further comprising dissolved phosphate anions released by the phosphate salt and dissolved fluoride anions released by the fluoride salt.