Morphinan derivative and its pharmaceutical applications

摘要

A morphinan derivative or its pharmacologically allowed acid addition salt represented with compound I,an analgesic and diuretic having its derivative or its salt as the active ingredient, and its production process are described. The compound of the present invention possesses strong analgesic activity and diuretic action as a highly selective kappa-opioid agonist, allowing it to be used as a useful analgesic and diuretic.