PHARMACEUTICAL COMPOSITIONS COMPRISING VIP-RELATED PEPTIDES FOR THE TREATMENT OF SEXUAL DISORDERS

摘要

The present invention relates to pharmaceutical compositions for the treatment of female sexual dysfunction, for vaginal relaxation and/or for modulation of sperm motility. The composition comprises as active ingredient (i) a peptide analogue or conjugate of vasoactive intestinal peptide (VIP) as defined in the specification and is preferably formulated for topical application in the vaginal, vulvar and/or clitorial area.The invention also relates to the use of the VIP peptide analogue or conjugate for the preparation of a pharmaceutical composition for the treatment of female sexual dysfunction, for vaginal relaxation and/or for modulation of sperm motility. Yet further, the invention provides a method of treatment of female sexual dysfunctions and/or vaginal relaxation by the use of said peptide analogue and/or conjugate.