CARBAPENEM DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF AND INTERMEDIATE COMPOUNDS

摘要

A carbapenem compound of the formula (I) wherein R<1> is a modifier hydrolyzable in the living body, R<2> and R<3> are the same or different and each is a lower alkyl, R is as defined in the specification. The carbapenem compound (I) of the present invention is superior in absorption from the digestive tract upon oral administration and shows sufficient antibacterial property against a broad range of bacteria species. Therefore, the compound is extremely useful for the prophylaxis and treatment of infectious diseases (particularly bacterial infection).