发明名称 |
Treatment of thrombosis by combined use of a factor XA inhibitor and aspirin, tissue plasminogen activator (TPA), a GPIIb/IIIa antagonist, low molecular weight heparin or heparin. |
摘要 |
Provided is a method of treating thrombosis in mammals by administering therapeutically effective amounts of a combination of (i) a Factor Xa inhibitor, and (ii) a compound selected from the group consisting of aspirin, TPA, a GPIIb/IIIa antagonist, low molecular weight heparin and heparin, wherein the dose administered for at least one of (i) and (ii) is a subtherapeutic dose. Preferably, the combination of (i) and (ii) provides a synergistic effect. |
申请公布号 |
ZA200106360(B) |
申请公布日期 |
2002.08.02 |
申请号 |
ZA20010006360 |
申请日期 |
2001.08.02 |
申请人 |
DU PONT PHARMACEUTICALS COMPANY |
发明人 |
PANCRAS C. WONG |
分类号 |
A61K31/19;A61K31/42;A61K31/44;A61K31/47;A61K31/60;A61K31/715;A61K38/02;A61K38/49;A61K45/06;A61P7/02;A61P9/12 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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