发明名称 |
Methods for the production of gelatin and full-length triple helical collagen in recombinant cells |
摘要 |
Methods are disclosed for simplified recombinant production of fibrillar collagens. DNAs encoding fibrillar collagen monomers lacking the N propeptide, the C propeptide, or both propeptides are introduced into recombinant host cells and expressed. Trimeric collagen is recovered from the recombinant host cells.
|
申请公布号 |
US6428978(B1) |
申请公布日期 |
2002.08.06 |
申请号 |
US19990289578 |
申请日期 |
1999.04.09 |
申请人 |
COHESION TECHNOLOGIES, INC.;GENOTYPES, INC. |
发明人 |
OLSEN DAVID R.;CHANG ROBERT;MCMULLIN HUGH;HITZEMAN RONALD A.;CHISHOLM GEORGE |
分类号 |
C12N15/09;C07K14/765;C07K14/78;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;(IPC1-7):C12P21/06;C07H21/02;C07H21/04;C07K14/00 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|