CRYSTALLINE FORM III AND IV OF N-BENZOYLSTAUROSPORINE

摘要

FIELD: pharmaceutics.SUBSTANCE: invention relates to a crystalline form III and a crystalline form IV of N-benzoyl staurosporine (midostaurin), pharmaceutical compositions based thereon.EFFECT: treatment of leukemia, acute lymphoblastic leukaemia, myelodysplastic syndromes and mastocytosis; preparing pharmaceutical composition by extrusion of melt.6 cl, 2 tbl, 4 dwg, 2 ex