发明名称 A method of producing a monoclonal antibody reactive to human cholesterol ester transfer protein
摘要 <p>A monoclonal antiboy that has a highly specific avidity with human-origin CETP (CETP inhibitory activity) and that is useful as a reagent for quantifying and purifying human-origin CETP and as a preventive or remedy for hyperlipemia and arteriosclerosis; and methods of quantifying and purifying human-origin CETP. The antibody permits the human-origin CETP contained in a sample to be quantified readily with a high sensitivity without the necessity for treating the sample with heat or surfactants. As the antibody has such a high CETP inhibitory activity, it is useful as medicines for treating or preventing, various diseases such as hyperlipemia, hyper-high-density-lipoproteinemia, hypercholesterolemia, and arteriosclerosis.</p>
申请公布号 IN188167(B) 申请公布日期 2002.08.31
申请号 IN1996CA78219 申请日期 1996.04.30
申请人 JAPAN TOBACCO INC. 发明人 KAMADA MASAFUMI;OKAMOTO HIROSHI;TAMATANI TAKUYA
分类号 A61K38/00;A61P3/10;A61P9/10;C07K16/18;C12P21/08;(IPC1-7):A61K39/00;C07K15/00 主分类号 A61K38/00
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