发明名称 |
Human DNA mismatch repair polynucleotides |
摘要 |
The present invention discloses three human DNA repair proteins and DNA (RNA) encoding such proteins. The DNA repair proteins may be produced by recombinant DNA techniques. One of the human DNA repair proteins, hmlh1, has been mapped on chromosome 3. The polynucleotide sequences of DNA repair proteins may be used for diagnosis of a hereditary susceptibility to cancer.
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申请公布号 |
US6482606(B1) |
申请公布日期 |
2002.11.19 |
申请号 |
US19940187757 |
申请日期 |
1994.01.27 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
ADAMS MARK D.;FLEISCHMANN ROBERT D.;FRASER CLAIRE M.;FULDNER REBECCA A.;KIRKNESS EWEN F.;HASELTINE WILLIAM A.;ROSEN CRAIG A.;RUBEN STEVE;WEI YING-FEI |
分类号 |
C07K14/47;(IPC1-7):C12P21/02;C12N1/00;C12N1/20;C12N5/10 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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