The invention relates to the field of vasculopathy and the diagnosis and treatment thereof. The invention provides a method for screening for a disease locus associated with vasculopathy in humans comprising testing genomic DNA via linkage analysis for the presence of a polymorphism or an allelic variation within a microsatellite region on chromosome 3p21.1-p21.3 and an isolated and/or recombinant nucleic acid, or fragment thereof, corresponding to or derived from a disease locus associated with vasculopathy which in humans is located on chromosome 3p21.1-p21.3.
申请公布号
WO03000890(A1)
申请公布日期
2003.01.03
申请号
WO2002NL00419
申请日期
2002.06.24
申请人
RIJKSUNIVERSITEIT TE LEIDEN;FRANTS, RUNE, ROBERT;FERRARI, MICHEL, DOMINIQUE;OPHOFF, ROEL;VAN DEN MAAGDENBERG, ARN
发明人
FRANTS, RUNE, ROBERT;FERRARI, MICHEL, DOMINIQUE;OPHOFF, ROEL;VAN DEN MAAGDENBERG, ARN