发明名称 |
AAV vectors |
摘要 |
The present invention is directed to a recombinant adenovirus vector comprising two inverted terminal repeats (ITRs) each of which comprises a D-sequence having (i) from 5 to 15 native nucleotides and (ii) one or more deletions or substitutions therein.
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申请公布号 |
US6521225(B1) |
申请公布日期 |
2003.02.18 |
申请号 |
US19970921497 |
申请日期 |
1997.09.02 |
申请人 |
CHIRON CORPORATION;ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE |
发明人 |
SRIVASTAVA ARUN;PONNAZHAGAN SELVARANGAN;CHLOEMER ROBERT H.;WANG XU-SHAN;YODER MERVIN C.;ZHOU SHANG-ZHEN;ESCOBEDO JAIME;DWARKI VARAVANI |
分类号 |
C12N15/09;A61K31/7088;A61K48/00;A61P1/16;C07K14/705;C12N15/864;C12Q1/68;(IPC1-7):A61K35/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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