发明名称 |
TRIAZOLE DIHYDROGEN PHOSPHATE DERIVATIVES |
摘要 |
<p>The invention provides compounds of formula I, <?in-line-formulae description="In-line Formulae" end="lead"?>R<SUP>1</SUP>-OP(O)(OH)<SUB>2</SUB> I<?in-line-formulae description="In-line Formulae" end="tail"?> wherein R<SUP>1 </SUP>represents the non-hydroxy portion of a triazole antifungal compound of the type comprising a tertiary hydroxy group; or a pharmaceutically acceptable salt thereof. The compounds of the invention are useful in the treatment of fungal infections, and have good aqueous solubility.</p> |
申请公布号 |
IL133135(A) |
申请公布日期 |
2003.07.06 |
申请号 |
IL19980133135 |
申请日期 |
1998.06.11 |
申请人 |
PFIZER RESEARCH AND DEVELOPMENT COMPANY |
发明人 |
|
分类号 |
C07D249/08;A61K31/00;A61K31/4196;A61K31/425;A61K31/675;A61P17/00;A61P31/00;A61P31/10;C07D403/10;C07D417/10;C07F;C07F9/6518;C07F9/6521;C07F9/6558;(IPC1-7):C07F9/651;C07F9/652;A61K31/419 |
主分类号 |
C07D249/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|