摘要 |
PROBLEM TO BE SOLVED: To provide a method of production for 1-(tert-butoxy-phenyl)-ω- haloalkane which is used as synthetic raw materials for effectively obtaining hydroxyphenylhaloalkane that is considered to be useful as a synthetic intermediate for fields such as a medicine, an agrochemical, a liquid crystal or the like, in high yield and high purity. SOLUTION: The 1-(tert-butoxyphenyl)-ω-haloalkane expressed by general formula (1) is obtained by reacting a dihaloalkane of general formula (3) to a tert-butoxyphenyl magnesium halide of general formula (2) in the presence of a cupper compound. (X is a halogen atom, X', Y' are each a chlorine atom or a bromine atom, n is an integer of 3-10.). COPYRIGHT: (C)2004,JPO
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