发明名称 Lead substances and their use as therapeutics
摘要 The present invention relates to peptides, which are useful in treating Staphylococcus infections. More particularly, the inventive peptides interfere with the regulation of the agr system of Staphylococcus species, especially S. aureus, and thereby block the formation of different virulence factors. The inventive peptides comprise at least the amino acid sequence S V X A S Y F, whereby cyclic structures of that kind of peptides are the most potent blocking reagents.
申请公布号 US6660835(B1) 申请公布日期 2003.12.09
申请号 US19980219865 申请日期 1998.12.24
申请人 GOETZ FRIEDRICH 发明人 OTTO MICHAEL;SUESSMUTH RODERICH;JUNG GUENTHER;GOETZ FRIEDRICH
分类号 A61K38/00;C07K7/06;C07K14/315;(IPC1-7):A61K38/08 主分类号 A61K38/00
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