发明名称 |
STABILIZED PHARMACEUTICAL COMPOSITIONS OF HALOFUGINONE AND OTHER QUINAZOLINONE DERIVATIVES |
摘要 |
The present invention relates to acid stabilized compositions containing as an active ingredient a quinazolinone derivative, preferably halofuginone or a pharmaceutically acceptable salt of halofuginone. More particularly the present invention relates to use of an acid for improving the stability of a topical, parenteral or oral composition containing quinazolinone derivatives as an active ingredient, preferably halofuginone. Surprisingly, even dry solid tablet dosage forms showed improved stability by addition of an acidic component. |
申请公布号 |
WO03070153(A3) |
申请公布日期 |
2003.12.24 |
申请号 |
WO2003IL00131 |
申请日期 |
2003.02.19 |
申请人 |
COLLGARD BIOPHARMACEUTICALS LTD.;YARKONI, SHAI;ZELIKOVICH, LIOR |
发明人 |
YARKONI, SHAI;ZELIKOVICH, LIOR |
分类号 |
C07D401/06;A61K9/00;A61K9/06;A61K9/08;A61K9/10;A61K9/107;A61K9/127;A61K9/14;A61K9/16;A61K9/20;A61K31/517;A61K47/00;A61K47/06;A61K47/10;A61K47/12;A61K47/14;A61K47/26;A61K47/34;A61K47/36;A61K47/38;A61K47/42;A61K47/44;A61P1/16;A61P11/00;A61P13/12;A61P17/00 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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