AGONISTS OF APOLIPOPROTEIN A-1 AND THEIR APPLICATION FOR TREATMENT OF DYSLIPIDEMIA-ASSOCIATED DISEASES

摘要

FIELD: medicinal biotechnology, medicinal biochemistry. SUBSTANCE: invention relates to peptides and peptide analogues that simulate structural and pharmacological properties of human apolipoprotein (ApoA- 1). Peptides and peptide analogues represent amino acid sequences and multimeric complexes with lipids that can be used for treatment of different diseases associated with dyslipidemia. Invention describes pharmaceutical compositions and methods for treatment based on simulating agents of ApoA-1. EFFECT: valuable medicinal properties of agonists, expanded assortment of agents for control of dyslipidemia. 52 cl, 10 tbl, 8 dwg, 12 ex