发明名称 PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS
摘要 Phenylalanine enamide derivatives of formula (1) are described: wherein R 1 , R x , R y , R z , X and V are as defined in claim 1. The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.
申请公布号 IL156915(D0) 申请公布日期 2004.02.08
申请号 IL20020156915 申请日期 2002.01.18
申请人 CELLTECH R&D LIMITED 发明人
分类号 A61K31/198;A61K31/4375;A61K31/44;A61K31/4406;A61K31/497;A61P3/10;A61P9/00;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P37/00;A61P37/06;A61P43/00;C07C229/34;C07C229/46;C07C233/82;C07C321/22;C07C323/30;C07D213/81;C07D213/89;C07D401/12;C07D405/12;C07D409/12;C07D413/12;C07D471/04;(IPC1-7):C07D 主分类号 A61K31/198
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