| 发明名称 |
METHOD FOR MAKING 3α-HYDROXY, 3β-METHYL-5α-PREGNAN-20-ONE (GANAXOLONE) |
| 摘要 |
Described is a method for the stereoselective and regioselective synthesis of 3α-hydroxy, 3β-methyl-5α-pregnan-20-one (ganaxolone) comprising reacting 5α-pregnane-3,20-dione with an organometallic methylating agent in an inert solvent to provide a compound of the formula |
| 申请公布号 |
EA024269(B1) |
申请公布日期 |
2016.09.30 |
| 申请号 |
EA20120070241 |
申请日期 |
2010.08.11 |
| 申请人 |
NOVAMEDICA LLC |
发明人 |
SHAW KENNETH;HUTCHISON ALAN |
| 分类号 |
C07J5/00;A61K31/57;A61K31/575;A61P25/28;C07J9/00 |
主分类号 |
C07J5/00 |
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