发明名称 |
DROPLET ACTUATOR DEVICES AND METHODS EMPLOYING MAGNETIC BEADS |
摘要 |
A method of providing a droplet in contact with a magnetically responsive bead and having a reduced quantity of a substance. The method generally includes the steps of (a) providing a droplet actuator (200) comprising: (i) a substrate (210) comprising electrodes (214) arranged for conducting droplet operations on a surface; (ii) a starting droplet (218/222) comprising: (1) one or more magnetically responsive beads (220); (2) a starting quantity of the substance; and (3) a starting volume; (b) magnetically immobilizing the one or more magnetically responsive beads at a location which is at a distance from a target droplet splitting zone, (224); (c) conducting one or more droplet operations comprising droplet dividing operations selected to divide the combined droplet to yield a set of droplets comprising: (i) a droplet (218) comprising substantially all of the one or more magnetically responsive beads and having a decreased quantity of the substance relative to the starting concentration; and (ii) a droplet (222) substantially lacking the magnetically responsive beads. |
申请公布号 |
CA2856143(C) |
申请公布日期 |
2016.11.01 |
申请号 |
CA20082856143 |
申请日期 |
2008.02.11 |
申请人 |
ADVANCED LIQUID LOGIC, INC. |
发明人 |
ECKHARDT, ALLEN E.;PAMULA, VAMSEE K.;POLLACK, MICHAEL G.;SISTA, RAMAKRISHNA;SRINIVASAN, VIJAY |
分类号 |
B01J19/12;B05B5/00;C07H21/00;C12M1/00;C12N1/00;C12N11/00;C12N15/00;C12Q1/00;G01N31/20;G01N33/48 |
主分类号 |
B01J19/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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