发明名称 |
P2Y4 antibody and methods of use |
摘要 |
This invention provides a receptor having a preference for pyrimidine nucleotides preferably uridine triphosphate over purine nucleotides. A receptor having a preference for pyrimidine nucleotides over purine nucleotides means a receptor for which pyrimidine nucleotides and purine nucleotides are not equally active and equipotent. This means that the receptor according to the invention in presence of these agonists presents a functional response (preferably the accumulation of Inositol triphosphate (IP3), diacylglycerol (DAG), or calcium ions) to lower concentration of pyrimidine nucleotides, preferably uridine triphosphate, than to purine nucleotides or a more important functional response to similar concentration of pyrimidine nucleotide than to purine nucleotide
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申请公布号 |
US2004259171(A1) |
申请公布日期 |
2004.12.23 |
申请号 |
US20040811198 |
申请日期 |
2004.03.26 |
申请人 |
EUROSCREEN, S.A. |
发明人 |
COMMUNI DIDIER;PIROTTON SABINE;PARMENTIER MARC;BOEYNAEMS JEAN-MARIE |
分类号 |
A01K67/027;A61K31/00;A61K31/70;A61K31/713;A61K38/17;A61K45/00;A61P43/00;C07K14/435;C07K14/705;C07K16/28;C12N5/10;C12N15/09;C12N15/11;C12N15/12;C12N15/85;C12N15/86;C12P21/08;C12Q1/68;G01N33/53;G01N33/577;(IPC1-7):G01N33/53;G01N33/567;A61K39/395 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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