| 发明名称 |
N-acil-sulfonamidas promotoras de apoptose |
| 摘要 |
"N-ACIL-SULFONAMIDAS PROMOTORAS DE APOPTOSE". Descreve-se N-benzoil-aril-sulfonamidas que têm a fórmula (I), são inibidores de BCL-X1, e úteis para promover apoptose. Descreve-se também composições e métodos inibidores de BCL-XL para promover apoptose em um mamífero.
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| 申请公布号 |
BR0110101(A) |
申请公布日期 |
2005.06.07 |
| 申请号 |
BR20010010101 |
申请日期 |
2001.09.20 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
WILLIAM MCCLELLAN;THORSTEN OOST;MILAN BRUNCKO;XILU WANG;DAVID J. AUGERI;STEVEN A. BAUMEISTER;DANIEL A. DICKMAN;HONG DING;JURGEN DINGES;STEPHEN W. FESIK;PHILIP J. HAJDUK;AARON R. KUNZER;DAVID G. NETTESHEIM;ANDREW M. PETROS;SAUL H. ROSENBERG;WANG SHEN;SHEELA A. THOMAS;MICHAEL D. WENDT |
| 分类号 |
A61K31/18;A61K31/428;A61K31/63;A61K31/635;A61P9/10;A61P25/16;A61P25/28;A61P29/00;A61P31/12;A61P31/18;A61P35/00;A61P37/02;C07C311/46;C07C311/51;C07C317/28;C07C323/12;C07C323/17;C07C323/25;C07C323/30;C07C323/37;C07C323/43;C07C323/44;C07C323/48;C07C323/58;C07C323/60;C07D203/10;C07D205/04;C07D205/12;C07D207/09;C07D207/24;C07D207/40;C07D207/404;C07D209/08;C07D209/52;C07D209/54;C07D209/96;C07D211/14;C07D211/44;C07D211/70;C07D211/74;C07D213/56;C07D213/61;C07D213/64;C07D213/69;C07D213/70;C07D213/71;C07D215/14;C07D215/22;C07D215/227;C07D215/38;C07D215/48;C07D217/04;C07D221/20;C07D231/12;C07D233/60;C07D235/08;C07D235/26;C07D241/08;C07D241/16;C07D249/04;C07D263/32;C07D263/56;C07D263/58;C07D277/62;C07D277/64;C07D295/13;C07D295/155;C07D295/16;C07D295/185;C07D295/20;C07D295/205;C07D295/215;C07D295/26;C07D307/14;C07D317/54;C07D333/28;C07D333/68;C07D333/70;C07D401/06;C07D401/12;C07D405/04;C07D405/06;C07D417/12;C07D451/02;C07D491/107;(IPC1-7):C07C311/00 |
主分类号 |
A61K31/18 |
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