Fremgangsmåde til fremstillingen af N-(phosphonomethyl)glycin ved oxidation af N-substitueret N-(phosphonomethyl)glycin

摘要

The present invention relates to a process for the preparation of an N-substituted N-(phosphonomethyl)glycine or a salt thereof, comprising: combining a source of H3PO3, a source of CH2O, and an N-substituted glycine salt; separating the resulting salt precipitate; adding a base to precipitate N-substituted N-(phosphonomethyl)glycine or the salt thereof; and separating the precipitated N-substituted N-(phosphonomethyl)glycine or salt thereof, wherein the N-substituted N-(phosphonomethyl)glycine has formula (I): R<1> and R<2> are independently selected from the group consisting of hydrogen, halogen, -PO3R<12>R<13>, -SO3R<14>, -NO2, hydrocarbyl, and substituted hydrocarbyl other than -CO2R<15>; R<6> is an agronomically acceptable cation; R<12>, R<13>, and R<14> are independently selected from the group consisting of hydrogen, hydrocarbyl, and substituted hydrocarbyl; and R<15> is selected from the group consisting of hydrogen, hydrocarbyl, substituted hydrocarbyl, and an agronomically acceptable cation.