| 发明名称 |
Substituted carbazoles as inhibitors of sPLA2 |
| 摘要 |
Carbazoles of formula (I) with R<SUP>2</SUP>=hydroxyfunctional amide (hydroxamic or esters) are disclosed together with the use of such compounds for inhibiting sPLA<SUB>2 </SUB>mediated release of fatty acids for treatment of conditions such as septic shock.
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| 申请公布号 |
US6933313(B2) |
申请公布日期 |
2005.08.23 |
| 申请号 |
US20030467965 |
申请日期 |
2003.08.14 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
HARPER RICHARD WALTZ;LIN HO-SHEN;RICHETT MICHAEL ENRICO |
| 分类号 |
A61K31/403;A61P1/04;A61P1/18;A61P9/10;A61P11/00;A61P11/06;A61P19/00;A61P19/02;A61P19/06;A61P25/28;A61P27/14;A61P29/00;A61P31/00;A61P43/00;C07D209/88;C07D403/12;C07D409/04;(IPC1-7):A61K31/403 |
主分类号 |
A61K31/403 |
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