发明名称 Integrin targeted imaging agents.
摘要 Emulsions preferably of nanoparticles formed from high bioling liquid perfluorochemical substances, said particles coated with a lipid/surfactant coating are made specific to regions of activated endothelial cells by coupling said nanoparticles to a ligand specific for QvP3 integrin, other than an antibody. The nanoparticles may further include biologically active agents, radionuclides, or other imaging agents.
申请公布号 ZA200406686(B) 申请公布日期 2005.09.19
申请号 ZA20040006686 申请日期 2004.08.23
申请人 BARNES JEWISH HOSPITAL;BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. 发明人 GREGORY LANZA;TOM HARRIS;WICKLINE, SAMUEL, A.
分类号 A61K47/22;A61K47/42;A61K47/48;A61K49/00;A61K49/18 主分类号 A61K47/22
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