发明名称 |
Integrin targeted imaging agents. |
摘要 |
Emulsions preferably of nanoparticles formed from high bioling liquid perfluorochemical substances, said particles coated with a lipid/surfactant coating are made specific to regions of activated endothelial cells by coupling said nanoparticles to a ligand specific for QvP3 integrin, other than an antibody. The nanoparticles may further include biologically active agents, radionuclides, or other imaging agents. |
申请公布号 |
ZA200406686(B) |
申请公布日期 |
2005.09.19 |
申请号 |
ZA20040006686 |
申请日期 |
2004.08.23 |
申请人 |
BARNES JEWISH HOSPITAL;BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. |
发明人 |
GREGORY LANZA;TOM HARRIS;WICKLINE, SAMUEL, A. |
分类号 |
A61K47/22;A61K47/42;A61K47/48;A61K49/00;A61K49/18 |
主分类号 |
A61K47/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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