发明名称 DERIVATIVES OF 1,4-DIAZABICYCLO[3,2,1]OCTANECARBOXAMIDE, PRODUCTION THEREOF AND USE IN THERAPY
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to derivatives of 1,4-diazabicyclo[3,2,1]octanecarboxamide with general formula (1) , in which X is a nitrogen atom, P and W each independently represent a nitrogen atom or a group with general formula C-R3, Q and R each independently represent a group with general formula C-R3, R1 is a hydrogen atom, R3 is a hydrogen atom or halogen or C1-C6-alkyl, C1-C6-alkoxy, O-Ms. The invention also relates to a medicinal preparation and pharmaceutical composition based on these compounds for treating or preventing disorders, related to malfunction of nicotinic receptors. ^ EFFECT: obtaining new compounds and a pharmaceutical composition based on the said compounds, which can be used for treating cognition failure and attention failure, or for treating motor, neurological or alerting symptoms related to dependency on different addictive substances. ^ 5 cl, 2 tbl, 4 ex
申请公布号 RU2361873(C2) 申请公布日期 2009.07.20
申请号 RU20060129633 申请日期 2005.01.07
申请人 SANOFI-AVENTIS 发明人 GALLI FREDERIK;LEKLERK ODIL';LOKKHED ALISTER
分类号 A61K31/416;A61K31/4162;A61K31/551;A61P9/00;A61P25/00;C07D487/08;C07D519/00 主分类号 A61K31/416
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