发明名称 CIS-FTC OF POLYMORPH AND OTHER CRYSTAL FORM
摘要 <p><P>PROBLEM TO BE SOLVED: To provide FTC of new polymorphic and other crystal form. <P>SOLUTION: A solid phase of amorphous (-)-FTC and (-)-cis-FTC called II and III(-)-cis-FTC which is distinguishable from I(-)-cis-FTC by its powder X-ray diffraction pattern, heat characteristic and production methods is provided. A hydrated crystal form of (±)-cis-FTC (that is, racemic cis-FTC) which is distinguishable from other form of FTC by its powder X-ray diffraction pattern, heat characteristic and production methods in a similar way, and a dehydrated form of the hydrate are also provided. These forms of FTC can be used for producing other forms of FTC or for a pharmaceutical composition. These forms are particularly desirably used for treating HIV or hepatitis B. <P>COPYRIGHT: (C)2009,JPO&INPIT</p>
申请公布号 JP2009197005(A) 申请公布日期 2009.09.03
申请号 JP20090097656 申请日期 2009.04.14
申请人 TRIANGLE PHARMACEUTICALS INC;ABBOTT LAB 发明人 PHARES KENNETH R;LAW DEVALINA;HU YUERONG
分类号 C07D411/04;A61K31/506;A61K31/513;A61P1/16;A61P31/18;A61P31/20 主分类号 C07D411/04
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