发明名称 TRACEABILITY OF CELLULAR CYCLE ANOMALIES TARGETING ONCOLOGY AND NEURODEGENERATION
摘要 The human LIV21 protein as a diagnostic and prognostic marker for various cancers and neurodegenerative diseases is provided. Methods for diagnosing and/or prognosing cancer utilizing the LIV21 protein and various derivatives and peptide fragments of the LIV21 protein are also provided.
申请公布号 US2017115296(A1) 申请公布日期 2017.04.27
申请号 US201615383251 申请日期 2016.12.19
申请人 FAURE Laurence 发明人 FAURE Laurence
分类号 G01N33/574 主分类号 G01N33/574
代理机构 代理人
主权项 1. A method for the detection of cancer cells in a biological sample from a patient, comprising detecting an expression product of the LIV21 gene in at least one of the nucleus and cytoplasm of cells in a sample of cells in the biological sample from said patient, the expression product comprising at least one peptide sequence selected from the group consisting of SEQ ID NO: 1-55, wherein localization of said expression product in the cytoplasm is indicative of the presence of said cancer cells in the biological sample, and localization of said expression product in the nucleus is indicative of the presence of non-cancerous cells in the biological sample.
地址 Paris FR