发明名称 |
MICRORNA BIOMARKER INDICATING ALZHEIMER'S DISEASE |
摘要 |
PROBLEM TO BE SOLVED: To provide a marker that is indicative of Alzheimer's Disease which may be used in diagnostic applications.SOLUTION: The invention provides a method for diagnosing Alzheimer Disease in a subject by determining the level of at least one miRNA in a sample taken from the subject. A change in the level of the at least one miRNA relative to a suitable control is indicative of Alzheimer's disease in the subject. A method for monitoring the course of Alzheimer's disease, a method for treating a subject having Alzheimer's Disease, and a kit for diagnosing Alzheimer's Disease are also provided.SELECTED DRAWING: None |
申请公布号 |
JP2016214256(A) |
申请公布日期 |
2016.12.22 |
申请号 |
JP20160150989 |
申请日期 |
2016.08.01 |
申请人 |
EISAI R & D MANAGEMENT CO LTD |
发明人 |
ZOLTAN DEZSO;PAVAN KUMAR |
分类号 |
C12Q1/68;A61K31/27;A61K31/445;A61K31/55;A61K45/00;A61P25/28;G01N33/50;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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