摘要 |
<p>1277847 Sulphonyl-ureas DR KARL THOMAE GmbH 16 April 1970 [17 April 1969 5 Jan 1970] 18242/70 Heading C2C Novel compounds I (including salts thereof) where R 1 is H, Cl, Br or C 1-4 alkoxy and R 2 is cyclohexyl or adamantyl are made by standard methods, especially utilizing compounds II {prepared, e.g. by reacting 2-(4-aminosulphonylphenyl)-ethylamine with a 1,2,3,4-tetrahydro- 4,4-dimethyl-7-R 1 -isochromane-1,3 -dione }. Pharmaceutical preparations showing hypoglycemic activity contain I as active ingredient; administration is, e.g. orally, parenterally or rectally.</p> |