发明名称 PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DE I-SOQUINOLEINA
摘要 <p>1277847 Sulphonyl-ureas DR KARL THOMAE GmbH 16 April 1970 [17 April 1969 5 Jan 1970] 18242/70 Heading C2C Novel compounds I (including salts thereof) where R 1 is H, Cl, Br or C 1-4 alkoxy and R 2 is cyclohexyl or adamantyl are made by standard methods, especially utilizing compounds II {prepared, e.g. by reacting 2-(4-aminosulphonylphenyl)-ethylamine with a 1,2,3,4-tetrahydro- 4,4-dimethyl-7-R 1 -isochromane-1,3 -dione }. Pharmaceutical preparations showing hypoglycemic activity contain I as active ingredient; administration is, e.g. orally, parenterally or rectally.</p>
申请公布号 ES378672(A1) 申请公布日期 1975.06.01
申请号 ES19720003786 申请日期 1970.04.16
申请人 KARL THOAME G. M. B. H. 发明人
分类号 A61K31/47;A61K31/64;C07D217/24;(IPC1-7):07D/;61K/ 主分类号 A61K31/47
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