摘要 |
1306726 Tetrahydropyranol derivatives F HOFFMANN-LA ROCHE & CO AG 12 May 1970 [13 May 1969] 56262/71 Divided out of 1306721 Heading C2C Compounds of the formula wherein Y is a grouping of the formula B is the remainder of a monocyclic or bicyclic aryl group which may carry one or more alkyl and/or alkoxy substituents, R<SP>5</SP> is a hydrogen atom or an alkyl group and R<SP>17</SP> is a hydrocarbylamino or dihydrocarbylamino group, the optical enantiomers thereof and the acid addition salts thereof, may be prepared by conventional methods. The products may exist in the open chain form of formula or as an equilibrium mixture of the two forms. In examples the products are obtained by reacting mono- or di-hydrocarbylamines with 11,11- arylene - dioxy - 7 - hydroxy - 1 - alken - 3 - ones which may be synthesized starting from 2,2- ethylenedioxy-5-chloropentane and glutaraldehyde. |