发明名称 Novel compound and pharmacological composition for controlling or preventing sickness states associated with intergrin Ó4 ß1
摘要 A method for the inhibition of the binding of .alpha.4.beta.1 integrin to it s receptors, for example vCAM-1 (vascular cell adhesion molecule-1) and fibro~ectin; compound s that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which .alpha.4.beta.1 is involved.
申请公布号 PL223151(B1) 申请公布日期 2016.10.31
申请号 PL20020356532 申请日期 2002.10.08
申请人 ENCYSIVE PHARMACEUTICALS INC 发明人 BIEDIGER RONALD J.;CHEN QI;HOLLAND GEORGE W.;KASSIR JAMAL M.;LI WEN;MARKET ROBERT V.;SCOTT IAN L.;WU CHENGDE;DECKER RADFORD E.;LI JIAN
分类号 C07D213/75;C07D221/04;A61K31/435;A61K31/44;A61K31/4412;A61K31/4704;A61K31/495;A61K31/50;A61K31/505;A61P1/00;A61P3/10;A61P9/10;A61P11/06;A61P19/02;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D207/416;C07D211/86;C07D213/02;C07D213/62;C07D213/69;C07D213/72;C07D215/22;C07D215/38;C07D221/16;C07D237/16;C07D237/22;C07D239/28;C07D239/46;C07D239/47;C07D317/46;C07D317/60;C07D401/04;C07D401/12;C07D403/12;C07D405/12;C07D409/06;C07D409/12;C07D409/14;C07D413/04;C07D413/06;C07D413/12;C07D417/06;C07D471/04;C07D498/04;C07K14/78 主分类号 C07D213/75
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