发明名称 |
SUBCUTAAN IMPLANTEERBARE PELLET. |
摘要 |
<p>A novel spherical implant pellet containing estradiol, estradiol benzoate, or mixtures thereof as the sole active ingredients which exhibits a substantially constant drug release rate over a timer period and substantially abrupt termination of drug release at the end of the time period is prepared which has an inert spherical core of a diameter of about 2-10 mm and a uniform coating of about 0.05-1 mm completely covering the core, the coating comprising about 5-99% suitable carrier and 1-95% drug. A drug may be administered at a constant rate over a chosen period by implanting the novel pellet and the release is substantially abruptly terminated at the end of said period without removing the pellet.</p> |
申请公布号 |
NL7604460(A) |
申请公布日期 |
1976.11.01 |
申请号 |
NL19760004460 |
申请日期 |
1976.04.27 |
申请人 |
SYNTEX (U.S.A.) INC. TE PALO ALTO, CALIFORNIE, VER.ST.V.AM. |
发明人 |
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分类号 |
A61K31/555;A61K9/00;A61K9/16;A61K9/22;(IPC1-7):61K9/22 |
主分类号 |
A61K31/555 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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