| 发明名称 | Antibacterial S-heterosubstituted disulfides | ||
| 摘要 | Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Francisella tularensis. The present invention provides compounds, methods and compositions effective to treat microbial/bacterial infections, and, especially, infections arising from bacteria which have developed resistance to conventional antibiotics. | ||
| 申请公布号 | US9512160(B2) | 申请公布日期 | 2016.12.06 |
| 申请号 | US201012765272 | 申请日期 | 2010.04.22 |
| 申请人 | University of South Florida | 发明人 | Turos Edward;Ramaraju Praveen |
| 分类号 | C07H15/00;C07C321/14;C07C321/20;C07C381/00 | 主分类号 | C07H15/00 |
| 代理机构 | Smith & Hopen, P.A. | 代理人 | Varkonyi Robert J.;Smith & Hopen, P.A. |
| 主权项 | 1. A compound having the formula (I): X1SSX2 (I) wherein each X1 and X2 are concurrently O—R1, or N-(1-phenylethyl)aniline; and wherein R1 is s-butyl, phenyl, | ||
| 地址 | Tampa FL US | ||