| 发明名称 |
Phenyl and benzodioxinyl substituted indazoles derivatives |
| 摘要 |
A compound of formula Ia:;;The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments |
| 申请公布号 |
US9512110(B2) |
申请公布日期 |
2016.12.06 |
| 申请号 |
US201414547809 |
申请日期 |
2014.11.19 |
| 申请人 |
AstraZeneca AB;Bayer Pharma Aktiengesellschaft |
发明人 |
Berger Markus;Rehwinkel Hartmut;Dahmen Jan;Eriksson Anders;Hansson Thomas;Hossain Nafizal;Klingstedt Per Tomas;Lepistö Matti;Nilsson Stinabritt;Hemmerling Martin;Edman Karl |
| 分类号 |
A61K31/416;C07D231/54;C07D409/14;C07D231/56;C07D401/12;C07D401/14;C07D403/10;C07D403/12;C07D405/12;C07D405/14;C07D409/12;C07D413/12;A61K31/4439;A61K45/06 |
主分类号 |
A61K31/416 |
| 代理机构 |
|
代理人 |
Barslow Kimberly D. |
| 主权项 |
1. A compound of formula Ib: wherein: A is C1-4alkyl, C1-4alkoxy or C1-4haloalkyl; R3 is C5-10heteroaryl; W is phenyl substituted by —C(O)NR7R8; R7 is hydrogen or C1-4alkyl; R8 is selected from hydrogen, C1-6alkyl (optionally substituted by one or two groups selected from hydroxyl, C5-10aryl and C5-10heteroaryl), C3-7 cycloalkyl (optionally substituted by hydroxyl), and C5-10heterocyclyl (optionally substituted by one or two groups selected from hydroxyl and oxo); or a pharmaceutically acceptable salt thereof. |
| 地址 |
Sodertalje SE |
