| 发明名称 |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF ECTODERMAL DYSPLASIA |
| 摘要 |
The invention relates to pharmaceutical compositions and methods for the treatment of ectodermal displasias via the administration of EDA agonists, in particular EDI200. Use of the compositions and methods described allow for therapeutic dosing and administration regimens in human patients to correct or alter abnormal phenotypes associated with genetic disorders, in particular, XLHED. |
| 申请公布号 |
US2016272694(A1) |
申请公布日期 |
2016.09.22 |
| 申请号 |
US201314442324 |
申请日期 |
2013.11.13 |
| 申请人 |
EDIMER PHARMACEUTICALS, INC. |
发明人 |
Huttner Kenneth M.;Kirby, Jr. Neil;Schneider Pascal;Gaide Olivier |
| 分类号 |
C07K14/705 |
主分类号 |
C07K14/705 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A pharmaceutical composition comprising at least one protein monomer, said protein monomer comprising SEQ ID NO: 1 and wherein said at least one protein monomer is glycosylated at positions Asn76 and Asn302 and a pharmaceutically acceptable excipient. |
| 地址 |
Cambridge MA US |
