Method for Synthesizing of Thioesters by Using Compound as Catalyst

摘要

A method for synthesizing of thioesters by using a compound as a catalyst is disclosed. The compound is represented by formula I below:;;In formula I, R5 represents H, a substituted or unsubstituted alkyl, a substituted or unsubstituted aryl, or a substituted or unsubstituted heteroaryl; X and Y each independently represents one of H, C1-10 alkyl, C5-10 aryl, C1-10 alkyl alcohol, thiohydroxy, carbonyl, sulfonyl, sulfamoyl, carbamoyl, C1-10 alkoxycarbonyl, C1-10 alkoxycarbamoyl, C1-10 alkylamino, C1-10 alkylsulfonyl, C1-10 haloalkylsulfonyl, ureido, amido, and C1-10 alkoxylcarbamoyl; and n is 0, 1, 2, 3, 4 or 5.

主权项

1. A method of synthesizing thioesters, using a compound as a catalyst, the compound represented by Formula (A) below: wherein, in Formula (A), R5 is independently selected from H, a substituted or unsubstituted alkyl, a substituted or unsubstituted aryl, or a substituted or unsubstituted heteroaryl; R11 is independently selected from a substituted or unsubstituted C1-C60 alkylene, a substituted or unsubstituted C3-C10 cycloalkylene, a substituted or unsubstituted C2-C10 heterocycloalkylene, a substituted or unsubstituted C2-C60 alkenylene, a substituted or unsubstituted C3-C10 cycloalkenylene, a substituted or unsubstituted C2-C10 heterocycloalkenylene, a substituted or unsubstituted C3-C10 cycloalkylene, a substituted or unsubstituted C6-C60 arylene, a substituted or unsubstituted C2-C60 heteroarylene, a substituted or unsubstituted divalent non-aromatic condensed polycyclic, a substituted or unsubstituted divalent non-aromatic condensed heteropolycyclic, —COO—, —O—, —(C═O)—, —N═N—, C═N—, —N—, —N(Q11)(Q12)-, —S—, —S(Q13)(Q14)-, —S(═O)—, or —S(═O)2—; R12 is independently selected from a halogen atom, a hydroxyl, a cyano, a nitro, a thiohydroxy, an amino, a carbonyl, a carbamoyl, a sulfamoyl, a substituted or unsubstituted C1-20 alkyl, a substituted or unsubstituted C2-C20 alkenyl, a substituted or unsubstituted C2-C20 alkynyl, a substituted or unsubstituted C1-C20 alkoxy, a substituted or unsubstituted C1-20 alkyl alcohol, a substituted or unsubstituted C1-20 haloalkyl, a substituted or unsubstituted C1-20 alkylthio, a substituted or unsubstituted C1-20 haloalkylthio, a substituted or unsubstituted C1-4 alkylamino, a substituted or unsubstituted C1-20 alkylamido, a substituted or unsubstituted C1-20 alkylsulfonyl, a substituted or unsubstituted C1-20 haloalkylsulfonyl, a substituted or unsubstituted C1-20 alkoxycarbonyl, a substituted or unsubstituted C1-20 alkylcarbamoyl, a substituted or unsubstituted C6-10 aryl, a substituted or unsubstituted C4-9 cycloalkyl, a substituted or unsubstituted C4-9 heteroaryl, and a substituted or unsubstituted C4-9 heterocycloalkyl; and a may be an integer selected from 0 to 10, wherein each of Q11 to Q14 is independently selected from a hydrogen, a deuterium, —F, —Cl, —Br, —I, a hydroxyl, a cyano, a nitro, an amino, an amidino, a hydrazine, a hydrazone, a carboxylic acid or a salt thereof, a sulfonic acid group or a salt thereof, a phosphoric acid group or a salt thereof, a C1-C60 alkyl, a C2-C60 alkenyl, a C2-C60 alkynyl, a C1-C60 alkoxy, a C3-C10 cycloalkyl, a C1-C10 heterocycloalkyl, a C3-C10 cycloalkenyl, a C2-C10 heterocycloalkenyl, a C6-C60 aryl, a C1-C60 heteroaryl, a monovalent non-aromatic condensed polycyclic group, or a monovalent non-aromatic condensed heteropolycyclic group.