摘要 |
Sulfoxides and sulfones of the formula WHEREIN R1 is COOH, COOR4, CH2OH, or CH2OR5; R2 is CH3 or C2H5; R3 is H, F, Cl, or Br; R4 is alkyl of 1-8 carbon atoms; R5 is alkanoyl of 2-4 carbon atoms; one of the Y groups is SO or SO2 and the other Y group is CH2, O, S, SO, or SO2; and the physiologically acceptable salts thereof, which compounds possess anti-inflammatory activity, can be produced by converting in a compound of the formula WHEREIN X is a group convertible into the group -CHR1R2 wherein R1, R2, R3, and Y have the values given above, the group X into the group -CHR1R3. |