| 发明名称 |
USE OF AMIDOXIME CARBOXYLIC ACID ESTERS AND N-HYDROXYGUANIDINE CARBOXYLIC ACID ESTERS FOR PRODUCING PRODRUGS |
| 摘要 |
The invention relates to a method for improving bioavailability of pharmaceutical substances and for allowing said pharmaceutical substances to permeate the blood-brain barrier, said pharmaceutical substances having at least one or more amidine, guanidine,N-hydroxyamidine (ami-doxime) or N-hydroxyguanidine-functions. The invention also relates to medicaments containing correspondingly modified pharmaceutical substances. |
| 申请公布号 |
CA2713784(C) |
申请公布日期 |
2016.09.27 |
| 申请号 |
CA20092713784 |
申请日期 |
2009.02.02 |
| 申请人 |
DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG |
发明人 |
CLEMENT, BERND;REEH, CHRISTIANE;HUNGELING, HELEN |
| 分类号 |
A61K31/155;A61P7/02;A61P9/12;A61P25/28;A61P31/16;A61P31/18;A61P33/02;A61P35/00 |
主分类号 |
A61K31/155 |
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