| 摘要 |
<p>PURPOSE:To prepar L-lysine in high yield, by culturing acetic acid-requiring variant of L-lysine-producing bacteria belonging to Brevibacterium genus, etc. CONSTITUTION:An acetic acid-requiring variant is induced from L-lysine-producing bacteria belonging to Brevibacterium genus or Corynebacterium genus, by irradiating with UV radiation or treating with N-methyl-N'-nitro-N-nitrosoguanidine, etc. The variant is aerobically cultured in an ordinary nutrient medium at 24-37 deg.C and pH5-9 for 2-7 days. L-lysine is separated from the medium in high yield by ion exchange resin treatment, etc.</p> |
